Table 1. Trabecular bone structural parameters are altered by Col3 deficiency.
Microcomputed tomography was used to assess quantitative parameters of trabecular bone structure in young and aged female mice. Data are displayed as the mean ± SD. Significant differences between Col3+/+ and Col3+/− mice are indicated
Female 6-8w | Female >ly | |||
---|---|---|---|---|
Col3+/+ (N=8) | Col3+./− (N=10) | Col 3+/+ (N=6) | Col3+/− (N=6) | |
BV | 0.04±0.01 | 0.03±0.01* | 0.04±0.01 | 0.02±0.01* |
TV | 0.33±0.02 | 0.31±0.01 | 0.34±0.05 | 0.32±0.05 |
BV/TV | 0.12±0.02 | 0.08±0.02* | 0.12±0.05 | 0.07±0.02* |
Conn. D. | 246.04±71.38 | 120.49±79.90* | 122.65±99.02 | 181.37±246.07 |
SMI | 2.92± 0.09 | 3.27±0.20** | 2.13±0.46 | 2.74±0.54 |
Tb.Th. | 0.033±0.0017 | 0.030±0.003* | 0.05±0.01 | 0.04±0.01 |