Table 3B.

Age- and African Ancestry-adjusted Odds Ratios (OR) and 95% Confidence Intervals (CI) for associations between VDR variants and Ovarian Cancer Risk among African Americans

	Cases				Controls		Age-and Ancestry-adjusted
	All*		Invasive**		All		All*		Invasive**
	N	(%)	N	(%)	N	(%)	OR	(95%CI)	OR	(95%CI)
rs7975232 Apa 1
AA	23	(31.1)	16	(29.1)	34	(43.0)
AC	36	(48.6)	27	(49.1)	41	(51.9)
CC	15	(20.3)	12	(21.8)	4	(5.1)
AC/CC	51	(68.9)	39	(70.9)	45	(57.0)
Log-additive							1.88	(1.14, 3.12)	2.08	(1.19, 3.63)
Total	74		55		79
rs2228570 Fok1
GG	47	(63.5)	35	(63.6)	54	(68.4)
AG	22	(29.7)	16	(29.1)	22	(27.8)
AA	5	(6.8)	4	(7.3)	3	(3.8)
AG/AA	27	(36.5)	20	(36.4)	25	(31.6)
Log-additive							1.25	(0.72, 2.16)	1.26	(0.70, 2.26)
Total	74		55		79
rs731236 Taq1
TT	43	(58.1)	32	(58.2)	43	(54.4)
TC	25	(33.8)	18	(32.7)	31	(39.2)
CC	6	(8.1)	5	(9.1)	5	(6.3)
TC/CC	31	(41.9)	23	(41.8)	36	(45.6)
Log-additive							0.95	(0.57, 1.59)	1.01	(0.58, 1.77)
Total	74		55		79
rs1544410 Bsm1
CC	44	(60.3)	34	(63.0)	38	(48.7)
CT	26	(35.6)	17	(31.5)	38	(48.7)
TT	3	(4.1)	3	(5.6)	2	(2.6)
CT/TT	29	(39.7)	20	(37.0)	40	(51.3)
Log-additive							0.72	(0.40, 1.29)	0.73	(0.39, 1.38)
Total	73		54		78
rs2239179
TT	34	(45.9)	27	(49.1)	40	(51.3)
TC	34	(45.9)	23	(41.8)	31	(39.7)
CC	6	(8.1)	5	(9.1)	7	(9.0)
TC/CC	40	(54.1)	28	(50.9)	38	(48.7)
Log-additive							1.09	(0.66, 1.82)	1.10	(0.64, 1.89)
Total	74		55		78
rs3782905
GG	49	(66.2)	37	(67.3)	49	(62.0)
GC	22	(29.7)	16	(29.1)	25	(31.6)
CC	3	(4.1)	2	(3.6)	5	(6.3)
GC/CC	25	(33.8)	18	(32.7)	30	(38.0)
Log-additive							0.81	(0.46, 1.41)	0.83	(0.45, 1.54)
Total	74		55		79
rs7968585
AA	26	(35.1)	19	(34.5)	25	(31.6)
AG	33	(44.6)	25	(45.5)	47	(59.5)
GG	15	(20.3)	11	(20.0)	7	(8.9)
AG/GG	48	(64.9)	36	(65.5)	54	(68.4)
Log-additive							1.20	(0.74, 1.94)	1.20	(0.71, 2.04)
Total	74		55		79

^*including all peritoneal cases

^**including serous invasive peritoneal cases