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. 2015 Feb 14;16(1):23. doi: 10.1186/s12931-015-0181-y

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© Diaz et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Plot of forced expiratory volume in 1 second (FEV ₁ ) as a function of the projected branching generation number. The figures shows the plot of forced expiratory volume in 1 second (FEV₁) to the projected branching generation number to reach <2 mm-lumen-diameter airways. Panels show the plots with the current study (Panel A), Weibel [20] (B), Mauroy [21] (C), and Montaudon’s [23] (D) lumen area ratios.