TABLE 2.
Patterns of failure.
| Patient | Primary site | T classification | N classification | p16 status | Smoking history | Margins | ECE | LVSI | PNI | Adjuvant | Recurrence site | Time to recurrence |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | BOT | 2 | 2b | pos | Yes | neg | neg | neg | neg | RT | Lung | 36 mo |
| 2 | Tonsil | 2 | 2b | neg | Yes | neg | neg | neg | neg | RT | Lung | 17.7 mo |
| 3 | Tonsil | 1 | 2b | pos | Yes | neg | neg | neg | neg | RT | Bone | 9.2 mo |
| 4 | Tonsil | 3 | 2b | pos | Yes | pos | pos | pos | neg | RT, C | Lung | 20.5 mo |
| 5 | Tonsil | 2 | 2b | neg | No | pos | pos | neg | neg | RT, C | Neck | 17.2 mo |
Abbreviations: ECE, extracapsular extension; LVSI, lymphovascular space invasion; PNI, perineural invasion; BOT, base of tongue; pos, positive; RT, radiation therapy; neg, negative; C, chemotherapy.