TABLE 2.
Life table for cumulative incidence of recurrent parasitemia in P. vivax patients treated with chloroquine-primaquine
| Day | Na | No. P. vivax positive (failure) | LFUb | IRc | CIRPd (95% CI) |
|---|---|---|---|---|---|
| 0 | 587 | 0 | 0 | 0 | 0 |
| 3 | 587 | 0 | 0 | 0 | 0 |
| 7 | 523 | 7 | 64 | 0.0143 | 1.43 (0.41–2.44) |
| 14 | 464 | 5 | 59 | 0.0115 | 2.56 (1.13–4.00) |
| 28 | 401 | 10 | 63 | 0.0271 | 5.20 (3.04–7.36) |
| 42 | 361 | 10 | 40 | 0.0293 | 7.98 (5.20–10.76) |
a
The number of patients remaining at risk on the indicated day post-study enrollment.
b
LFU, number of patients lost to follow-up
c
IR, interval risk, calculated as i[N − (LFU/2)]−1.
d
CIRPn, the cumulative incidence of recurrent parasitemia, calculated as follows: 1 − {[1 − IRn] × [1 − CIRP(n − 1)]}, where n is the day of the test and n − 1 is the prior interval.