TABLE 3.
MICs of 10 antibiotics against M. pneumoniae clinical strains and the FH strain
| Isolate groupa | MIC (μg/ml)b |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ERY | CLR | AZM | JOS | RKI | MIN | DOX | LVX | CIP | GAT | |
| Clinical isolates (A2063G) | 128 to >256 | 128 to >256 | 32 to >64 | 1 to 8 | 0.064 to 1 | 0.031 to 1 | 0.125 to 1 | 0.25 to 2 | 0.5 to 2 | 0.016 to 0.125 |
| Reference strain FH | 0.016 | 0.008 | 0.002 | 0.063 | 0.01 | 0.031 | 0.063 | 0.5 | 1 | 0.125 |
a
As characterized by mutation in the 23S rRNA gene.
b
Abbreviations: ERY, erythromycin; CLR, clarithromycin; AZM, azithromycin; JOS, josamycin; RKI, rokitamycin; DOX, doxycycline; MIN, minocycline; LVX, levofloxacin; CIP, ciprofloxacin; GAT, gatifloxacin. MIC ranges are given for the clinical iolates.