TABLE 1.

Activity of ABT-450 against replicon cell lines with NS3 from different genotypes in the presence or absence of 40% human plasma

Human plasma concn (%)	EC50 (nM, mean ± SD) with genotype:
	1a	1b	2a	3a	4a	6a
0	1.0 ± 0.33	0.21 ± 0.07	5.3 ± 1.2	19 ± 5.2	0.09 ± 0.03	0.69 ± 0.09
40	17.3 ± 5.7	5.2 ± 2.0	NDa	ND	ND	ND

^aND, not determined.