TABLE 3.
Concentration of avibactam required to reach a given MIC of ceftazidime for the median and 90th percentile of strains
Ceftazidime target MIC (mg/liter) | MICs of avibactam (50th/90th percentiles [mg/liter]) for: |
|||
---|---|---|---|---|
P. aeruginosa (n = 18) | Enterobacteriaceae all (n = 51) | E. coli (n = 18) | K. pneumoniae (n = 29) | |
1 | 32/≥64 | 1/4 | 0.031/2 | 2/8 |
4 | 4/16 | 0.063/1 | 0.016/0.063 | 0.250/1 |
8 | 1/8 | 0.031/0.25 | 0.016/0.031 | 0.125/0.5 |