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. 2015 Jan 27;59(2):1061–1069. doi: 10.1128/AAC.03947-14

TABLE 1.

Anti-influenza activity of nitazoxanidea

PR8 virus yield IC50 (μM) LD50 (μM) SI
HAU/ml 3.2 ± 0.0 >163.0 >50.9
TCID50/ml 4.1 ± 0.2 >163.0 >39.8
PFU/ml 1.3 ± 0.1 >163.0 >125.4
a

PR8 IAV yield was determined at 24 h p.i. by HA titration, TCID50 infectivity assay, and plaque assay. Data are the means ± SD of results from quadruplicate samples.