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Ecumicin spectrum of activities
| Target | MIC (μM) ofa: |
IC50 (μM) of: |
|||||
|---|---|---|---|---|---|---|---|
| ECM | RMP | CAP | MFX | KM | ECM | RMP | |
| E. faecalis | >32 | 12 | |||||
| P. aeruginosa | >32 | 0.10 | |||||
| S. pneumonias | >32 | 0.05 | |||||
| A. baumannii | >32 | ||||||
| E. coli | >32 | >50 | |||||
| S. aureus | >32 | >50 | |||||
| C. albicans | >32 | >50 | |||||
| M. smegmatis | 1.7 | 12 | 49 | 0.48 | 0.48 | ||
| M. chelonae | 0.97 | ||||||
| M. abscessus | >63 | ||||||
| M. kansasii | <0.24 | ||||||
| M. avium | 0.35 | ||||||
| M. marinum | 0.95 | ||||||
| Vero cells | >63 | 86 | |||||
| J774 cells | >32 | ||||||
ECM, ecumicin; RMP, rifampin; CAP, capreomycin; MFX, moxifloxacin; KM, kanamycin.
