FIGURE 2 —

Potential differentiation of mesothelial progenitor cell during PD. A subpopulation of mesothelial progenitor cells rest in the peritoneum, possessing the capability of multipotential differentiation. These cells, when triggered by PD-related stimuli, can differentiate toward interstitial (myo)fibroblasts and endothelial cells, contributing to a pool of fibroblasts and angiogenesis during peritoneal dialysis. PD = peritoneal dialysis; MC = mesothelial cell; MPC = mesothelial progenitor cell; FB = fibroblast; EC = endothelial cell; MFB = myofibroblast.