Table 1. Published studies comparing the oncologic outcomes after fertility-sparing surgery for BOTs.
| Authors | Patients (n) | Surgical procedure | Recurrence n (%) | Histology of recurrence | Interval to recurrence (mo) | Death (n) | F/u (mo) |
|---|---|---|---|---|---|---|---|
| Zanetta et al (2001) | 189 | C 50 USO 139 |
14 (28%) 21 (15.1%) |
9-BOT, 5-IOC 20-BOT, 1-IOC |
39 45 |
1 | 70 |
| Song et al (2011) | 155 | C 38 USO 117 |
5 (13.2%) 7 (5.9%) |
5-BOT 6-BOT, 1-IOC |
28 42 |
0 | 56 |
| Yinon et al (2007) | 62 | C 22 USO 40 |
5 (22.7%) 11 (27.5%) |
5-BOT 10-BOT |
23.6 41 |
0 | 88 |
| Morice et al (2001) | 44 | C 11 USO 33 |
4 (36.3%) 5 (15.1%) |
4-BOT 5-BOT |
- | 0 | 109 |
| Park et al (2009) | 184 | C 56 USO 128 |
6 (10.7%) 3 (2.3%) |
6-BOT 2-BOT, 1-IOC |
10 49.5 |
1 | 70 |
| Boran et al (2005) | 62 | C 22 USO 40 |
3 (13.6%) 1 (2.5%) |
3 BOT 1 BOT |
24 48 |
0 | 44.3 |
| Donnez et al (2003) | 16 | C 5 USO 11 |
1 (20%) 2 (18.2%) |
1 BOT 2 BOT |
12 21 |
0 | 43.4 |
| Seracchioli et al (2001) | 19 | C 11 USO 8 |
1 (9%) 0 |
1 BOT | 6 | 0 | 42 |
| Gotlieb et al (1998) | 39 | C 12 USO 27 |
2 (16.6%) 2 (7.4%) |
2 BOT 1 BOT, 1 IOC |
82.5 33 |
0 | 70 |
| Camatte et al (2002) | 68 | C 21 USO 47 |
4 (19%) 5 (10.6%) |
4 BOT 5 BOT |
- | 0 | 71 |
| Longacre et al (2005) | 53 | - | 9 (17%)* | 7 BOT, 2 IOC* | - | 0 | 60 |
| Fauvet et al (2005) | 162 | - | 27 (17%)* | 27 BOT* | 39* | 0 | - |
| Romagnolo et al (2006), | 53 | C 21 USO 32 |
6 (28.6%) 7 (21.9%) |
6 BOT 7 BOT |
- | 1 | 44 |
| Wong et al (2007) | 116 | C 38 USO 78 |
2 (5.3%) 2 (2.3%) |
2 BOT, 2 IOC* | 59* | 1 | 21 |
| Kanat-Pektas et al (2011) | 55 | C 19 USO 36 |
2 (10.5%) 1 (2.8%) |
2 BOT 1 BOT |
- | 0 | 61 |
| Khunamornpong et al (2011) | 60 | C 1 USO 59 |
6 (10%)* | 2 BOT, 4 IOC* | - | 2 | - |
C: Cystectomy
USO: Unilateral salpingo-oophorectomy
IOC: Invasive ovarian cancer
*
Data is not divided by type of surgery