Table 2. Plasma gold levels from Brugia infected gerbils following necropsy.
| Time after last dose | Plasma gold levels (ug/L) | Concentration of gold (uM) | ||
|---|---|---|---|---|
| Study #1 | Aur1 | 2 hours* | 1700 | 8.631 |
| Aur2 | 2 hours* | 1000 | 5.077 | |
| Aur3 | 11 days | 270 | 1.371 | |
| Aur4 | 14 days | 340 | 1.726 | |
| Aur5 | 16 days | 160 | 0.812 | |
| Aur6 | 16 days | 170 | 0.863 | |
| Aur7 | 16 days | 0 | 0 | |
| Aur8 | 16 days | 170 | 0.863 | |
| Aur9 | 16 days | 190 | 0.965 | |
| Study #2 | Aur1 | 16 days | 130 | 0.660 |
| Aur2 | 16 days | 190 | 0.965 | |
| Aur3 | 16 days | 0 | 0 | |
| Aur4 | 16 days | 160 | 0.812 |
* Plasma taken at interim necropsy, two hours after last dose (following 14 days of treatment).