Table 1.
No BOS (N=117) | BOS (N=92) | Combined (N=209) | P-value | ||||
---|---|---|---|---|---|---|---|
Single Transplant | 43 | 37% | 36 | 39% | 79 | 38% | 0.73 |
Diagnosis | 0.59 | ||||||
Cystic fibrosis/bronchiectasis | 8 | 7% | 4 | 4% | 12 | 6% | |
Obstructive | 41 | 35% | 38 | 41% | 79 | 38% | |
Restrictive | 64 | 55% | 45 | 49% | 109 | 52% | |
Vascular | 4 | 35% | 5 | 5% | 9 | 4% | |
Aspergillus Episodes | 0.008 | ||||||
0 | 76 | 65% | 37 | 40% | 113 | 54% | |
1 | 22 | 19% | 34 | 37% | 56 | 27% | |
2 | 14 | 11% | 11 | 12% | 25 | 12% | |
3 | 2 | 2% | 2 | 2% | 4 | 2% | |
4 | 2 | 2% | 2 | 2% | 4 | 2% | |
6 | 1 | 1% | 4 | 5% | 5 | 2% | |
8 | 0 | 0% | 2 | 2% | 2 | 1% | |
Pseudomonas Episodes | 0.002 | ||||||
0 | 90 | 76% | 46 | 50% | 136 | 65% | |
1 | 15 | 13% | 20 | 22% | 35 | 17% | |
2 | 5 | 4% | 12 | 13% | 17 | 8% | |
3 | 2 | 2% | 0 | 0% | 2 | 1% | |
4 | 2 | 2% | 7 | 8% | 9 | 4% | |
5 | 2 | 2% | 5 | 5% | 7 | 3% | |
7 | 1 | 1% | 1 | 1% | 2 | 1% | |
8 | 0 | 0% | 1 | 1% | 1 | 0% | |
Pseudomonas Colonization | 0.016 | ||||||
0 | 92 | 78% | 51 | 56% | 143 | 69% | |
1 | 13 | 11% | 20 | 22% | 33 | 16% | |
2 | 3 | 6% | 10 | 11% | 17 | 8% | |
3 | 0 | 0% | 4 | 4% | 4 | 2% | |
4 | 7 | 3% | 4 | 4% | 7 | 3% | |
5 | 1 | 1% | 2 | 2% | 3 | 1% | |
7 | 1 | 1% | 1 | 1% | 2 | 1% | |
Pseudomonas Infection | 0.003 | ||||||
0 | 112 | 96% | 74 | 81% | 186 | 89% | |
1 | 5 | 4% | 12 | 13% | 17 | 9% | |
2 | 0 | 0% | 3 | 3% | 3 | 1% | |
3 | 0 | 0% | 3 | 3% | 3 | 1% | |
Acute Rejection Episodes | 0.06 | ||||||
0 | 51 | 43% | 27 | 29% | 78 | 37% | |
1 | 36 | 31% | 29 | 32% | 65 | 31% | |
2 | 18 | 15% | 17 | 18% | 35 | 16% | |
3 | 10 | 9% | 7 | 8% | 17 | 8% | |
4 | 2 | 2% | 7 | 8% | 9 | 4% | |
5 | 0 | 0% | 3 | 3% | 3 | 2% | |
7 | 0 | 0% | 1 | 1% | 1 | 1% | |
9 | 0 | 0% | 1 | 1% | 1 | 1% | |
Staph Episodes | 0.60 | ||||||
0 | 87 | 74% | 60 | 65% | 147 | 71% | |
1 | 19 | 16% | 21 | 23% | 40 | 19% | |
2 | 8 | 7% | 8 | 9% | 16 | 8% | |
3 | 1 | 1% | 2 | 2% | 3 | 1% | |
4 | 2 | 2% | 1 | 1% | 3 | 1% | |
Time to BOS/Censored | <0.001 | ||||||
Lower quartile | 693 | 405 | 531 | ||||
Median | 1028 | 651 | 828 | ||||
Upper quartile | 1533 | 945 | 1354 | ||||
Median SD | (1153+/−689) | (739+/−449) | (971 +/− 629) | ||||
Time from Transplant to Death/Censored | |||||||
Lower quartile | 693 | ||||||
Median | 1028 | ||||||
Upper quartile | 1533 | ||||||
Median SD | (1153+/−689) | ||||||
Time from BOS to Death/Censored | |||||||
Lower quartile | 155 | ||||||
Median | 333 | ||||||
Upper quartile | 741 | ||||||
Median SD | (476+/−430) |