Table 2.
Transition from State 1 to State 2 (Post-transplantation to BOS). This model includes CXCL5 and the interaction between staphylococcus and CXCL5.
| Significance of Covariates | P-value | |||
|---|---|---|---|---|
| Transplant Type | 0.167 | |||
| Aspergillus Status | 0.181 | |||
| Acute Rejection Status | 0.005 | |||
| Pseudomonas Status | 0.008 | |||
| Staph Status | 0.962 | |||
| CXCL5 level | 0.021 | |||
| Staph Status * CXCL5 level | 0.047 | |||
| Covariate Effects Testing | HR | Lower Limit | Upper Limit | P-value |
| Transplant:Single vs Double | 1.35 | 0.88 | 2.08 | 0.167 |
| Aspergillus: Yes vs None | 1.37 | 0.86 | 2.16 | 0.181 |
| Acute Rejection: Yes vs None | 1.92 | 1.22 | 3.00 | 0.005 |
| Pseudumonas Overall: Yes vs None | 1.89 | 1.18 | 3.01 | 0.008 |
| Staph: Yes vs None, at CXCL5 50 pg/mL | 1.03 | 0.64 | 1.65 | 0.915 |
| Staph: Yes vs None, at CXCL5 100 pg/mL | 1.07 | 0.67 | 1.71 | 0.790 |
| Staph: Yes vs None, at CXCL5 200 pg/mL | 1.15 | 0.72 | 1.83 | 0.558 |
| Staph: Yes vs None, at CXCL5 600 pg/mL | 1.56 | 0.89 | 2.72 | 0.122 |
| Staph: Yes vs None, at CXCL5 1200 pg/mL | 2.45 | 1.00 | 5.96 | 0.049 |
| Staph: Yes vs None, at CXCL5 1600 pg/mL | 3.31 | 1.04 | 10.51 | 0.042 |
| Staph: Yes vs None, at CXCL5 2000 pg/mL | 4.48 | 1.07 | 18.79 | 0.040 |
| Difference in the effect of having Staph present, at CXCL5=200 vs at CXCL5=25 | 1.16 | 1.02 | 1.32 | 0.026 |
| Difference in the effect of having Staph present, at CXCL5=400 vs at CXCL5=25 | 1.37 | 1.04 | 1.81 | 0.026 |
| Effect of CXCL5 per 100 pg/mL increase, when Staph not present (Staph = No) | 1.01 | 1.00 | 1.02 | 0.021 |
| Effect of CXCL5 per 100 pg/mL increase, when Staph is present (Staph = Yes) | 1.09 | 1.01 | 1.17 | 0.026 |
| Difference in the effect of CXCL5 per 100 pg/mL increase, when Staph=Yes vs when Staph=No | 1.08 | 1.00 | 1.16 | 0.047 |