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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Laryngoscope. 2014 Nov 28;125(3):E118–E124. doi: 10.1002/lary.25056

Figure 1. Sensitivity of three human HNSCC cell lines to birinapant or docetaxel in vitro.

Figure 1

Percent inhibition of cell density with birinapant ± TNF or TRAIL, A, and docetaxel, B, over a range of concentrations was determined during log growth phase on day 3 by XTT assay. Data points from 6 replicates per concentration were used to compare to controls to calculate percentages of inhibition. The mean and SD were plotted and shown, with IC50 determined by non-linear four parametric regression. TNF or TRAIL enhanced curves were significantly different from birinapant alone (p<0.01).