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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Laryngoscope. 2014 Nov 28;125(3):E118–E124. doi: 10.1002/lary.25056

Figure 3. Combination effects of birinapant and docetaxel.

Figure 3

Percent growth inhibition was assessed by XTT on day 3 post-treatment with varying doses of birinapant ± TNF, docetaxel, or birinapant ± TNF + docetaxel in fixed ratios. A, Cell density relative to untreated control cells after treatment with birinapant (B), docetaxel (D), or combination (B+D) (*p<0.05, **p<0.01, ***p<0.001; t-test). B, Results were analyzed for synergism using CompuSyn software, in which Combination Index (CI) <0.9 denotes synergism (below dashed line); CI 0.9–1.1, additive; CI >1.1, antagonism.