TABLE 4.
Quantitative Viral Replication in Urine, Oral Wash, and Blood in Donors at Transplant and Recipients Posttransplant among 98 Donor and Recipient Pairs *, **
| AT TRANSPLANT | POST-TRANSPLANT | |||
|---|---|---|---|---|
|
| ||||
| KIDNEY (N=83) | ||||
|
| ||||
| Donor EBV replication in Blood/Urine/Oral Wash | Recipient EBV Replication in Urine/Oral Wash | Recipient EBV viremia | ||
|
| ||||
| Positive (n=21)
|
4 (19%) | p 0.45 | 6 (29%) | p 0.38 |
| Negative (n=62) | 17 (27%) | 12 (19%) | ||
|
| ||||
| Donor BKV replication in Blood/Urine/Oral Wash | Recipient BKV Replication in Urine/Oral Wash | Recipient BKV viremia | ||
|
| ||||
| Positive (n=15)
|
7 (47%) | p 0.12 | 5 (33%) | p 0.02*** |
| Negative (n=68) | 18 (26%) | 7 (10%) | ||
|
| ||||
| LIVER (N=15) | ||||
|
| ||||
| Donor EBV replication in Blood/Urine/Oral Wash | Recipient EBV Replication in Urine/Oral Wash | Recipient EBV viremia | ||
|
| ||||
| Positive (n=1)
|
0 | p 0.69 | 0 | p 0.69 |
| Negative (n=14) | 2 (14%) | 2 (14%) | ||
|
| ||||
| Donor BKV replication in Blood/Urine/Oral Wash | Recipient BKV Replication in Urine/Oral Wash | Recipient BKV viremia | ||
|
| ||||
| Positive (n=2)
|
0 | p 0.55 | 0 | p 0.55 |
| Negative (n=13) | 2 (15%) | 2 (15%) | ||
*
There was no donor replication of CMV and therefore its impact on recipient CMV viral replication/viremia could not be demonstrated
**
Only 2 donors had EBV viremia and 1 donor had BKV viremia. Therefore the impact of donor EBV and BKV viremia on recipient viral replication is not shown separately. The kidney recipients of the donor that had isolated EBV viremia as well as of the donor that had isolated BKV viremia at the time of transplant did not have posttransplant BKV replication in urine/oral wash or blood.
***
p<0.05 is considered significant