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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Pediatr Infect Dis J. 2015 Jan;34(1):55–61. doi: 10.1097/INF.0000000000000526

TABLE 4.

Relation between the change in pre-ART to 6-month post-ART immune, viral, and growth parameters and age at walking and speech

Walking (N=54) Speech (N=53)

Change from pre-ART to 6 months post-ART RC (95% CI) (P-value) Adj. RC (95% CI) (P-value) RC (95% CI) (P-value) Adj. RC (95% CI) (P-value)
CD4%, per unit increase −0.14 (−0.24, −0.04) (0.006) −0.18 (−0.30, −0.06) (0.004) −0.06 (−0.16, 0.04) (0.2) −0.12 (−0.23, −0.003) (0.05)
Plasma HIV RNA per log10 copies/mm3 increase* 0.17 (−0.45, 0.79) (0.6) 0.29 (−0.38, 0.95) (0.4) 0.23 (−0.34, 0.82) (0.4) 0.52 (−0.06, 1.10) (0.08)
WAZ, per SD increase 0.16 (−0.46, 0.78) (0.6) −0.94 (−1.64, −0.24) (0.009) 0.48 (−0.09, 1.05) (0.09) −0.29 (−0.98, 0.40) (0.4)
HAZ, per SD increase 0.14 (−0.74, 1.03) (0.7) −1.34 (−2.54, −0.14) (0.03) 0.53 (−0.29, 1.35) (0.2) −.85 (−1.95, 0.25) (0.1)
WHZ, per SD increase −0.003 (−0.58, 0.57) (1.0) −0.79 (−1.46, −0.12) (0.02) 0.14 (−0.40, 0.69) (0.6) −0.20 (−0.88, 0.48) (0.6)
HCZ, per SD increase* −0.30 (−1.23, 0.63) (0.5) −0.98 (−2.14, 0.19) (0.1) 0.7 (−0.17, 1.58) (0.1) 0.48 (−0.64, 1.60) (0.4)
*

N=49 for analysis of HIV RNA and walking and N=48 for analysis of HIV RNA and speech; N=52 for analysis of HCZ and speech.

RC, regression coefficient; CI, confidence interval; SD, standard deviation; WAZ, weight-for-age z-score; HAZ, height-forage z-score; WHZ, weight-for-height z-score; HCZ, head circumference-for-age z-score.