Table 3.

Main fatty acids (≥0.5%) from total lipids (weight %) of plasma from a human randomized controlled trial where participants consumed an elderberry extract or a placebo for 12 weeks.

Fatty acid	Control		Elderberry		P valuea
	Week 0	Week 12	Week 0	Week 12	Time	ACN	T×ACN
14:0	10.62±4.5	9.05±4.8	8.76±3.0	8.45±4.7	NS	NS	NS
16:0	18.82±1.6	18.58±1.5	19.53±1.6	20.33±1.5	NS	0.014	NS
16:1b	2.01±0.5	2.25±0.6	2.43±0.6	2.76±0.7	NS	0.010	NS
18:0	6.95±0.6	6.97±0.5	6.77±0.8	7.41±1.0	NS	NS	NS
18:1b	17.96±2.0	18.00±2.2	19.14±1.7	18.96±2.6	NS	NS	NS
18:2n6	24.64±4.0	25.90±3.2	24.52±3.8	22.48±3.5	NS	NS	NS
18:3n3	0.49±0.2	0.67±0.2	0.59±0.2	0.65±0.2	0.015	NS	NS
20:3n6	1.42±0.5	1.31±0.3	1.34±0.6	1.34±0.3	NS	NS	NS
20:4n6	5.38±1.7	5.53±1.4	5.91±1.8	5.28±1.3	NS	NS	NS
20:5n3	1.29±0.7	1.31±1.0	0.99±0.5	1.31±1.1	NS	NS	NS
22:5n3	0.60±0.1	0.58±0.1	0.58±0.2	0.58±0.2	NS	NS	NS
22:6n3	2.67±0.7	2.51±0.9	2.37±0.6	2.49±1.0	NS	NS	NS
Total n-3 PUFA	1.26±0.3	1.27±0.5	1.13±0.3	1.26±0.5	NS	NS	NS
Total n-6 PUFA	4.61±0.7	4.84±0.6	4.67±0.5	4.39±0.6	NS	NS	NS
n-3/n-6 PUFA ratio	0.28±0.1	0.26±0.1	0.24±0.1	0.29±0.1	NS	NS	NS
Δ6 (18:3 n-6/18:2 n-6)	0.02±0.0	0.02±0.0	0.02±0.0	0.03±0.0	0.017	NS	NS

Values are means±S.D. (n=13). Totals include some minor components not shown.

^aTwo-way ANOVA: time, significant influence of duration of the trial; ACN, significant influence of ACNs; T×ACN, interaction; NS, not significant (P>.05).

^bContains n-9 and n-7 isomers.