Table 2.
Ventilation, oxygenation, and hemodynamic variables throughout the first 40 h of the prone positioning
| Supine | 8 h | 16 h | 24 h | 32 h | 40 h | p value | |
|---|---|---|---|---|---|---|---|
| HR | 89.7 ± 18.2 | 88.8 ± 20.3 | 85.6 ± 20.0 | 89.7 ± 19.0 | 89.3 ± 22.5 | 84.3 ± 17.2 | 0.95 |
| MBP | 78.9 ± 14.7 | 80.6 ± 10.1 | 77.4 ± 14.4 | 75.8 ± 14.5 | 80.1 ± 19.2 | 75.5 ± 13.9 | 0.90 |
| FiO2 | 0.62 ± 0.19 | 0.50 ± 0.13 | 0.51 ± 0.12 | 0.48 ± 0.09 | 0.46 ± 0.09 | 0.46 ± 0.09 | 0.002 |
| PEEP | 13.4 ± 6.9 | 13.5 ± 6.4 | 13.5 ± 6.4 | 13.9 ± 6.5 | 12.9 ± 6.5 | 12.4 ± 6.0 | 0.99 |
| PFR | 193.8 ± 70.1 | 274.7 ± 70.7 | 294.1 ± 78.0 | 289.0 ± 88.1 | 294.6 ± 68.2 | 291.7 ± 72.7 | 0.002 |
| PaCO2 | 43.8 ± 7.7 | 47.5 ± 8.0 | 46.0 ± 13.6 | 44.9 ± 10.6 | 46.3 ± 8.9 | 47.2 ± 8.5 | 0.91 |
Values are expressed as the mean ± standard deviation. ANOVA was used to compare values among the various time points. Supine represents immediately before starting prone positioning. HR heart rate, MBP mean blood pressure, PEEP positive end-expiratory pressure, PFR PaO2/FiO2 ratio.