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. 2015 Feb 20;10(2):e0117115. doi: 10.1371/journal.pone.0117115

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© 2015 Liu et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 1 — A: Homology between the amino acid sequences of SreA from P. digitatum and SrbA in A. fumigatus. The sequence under the red line indicates basic helix-loop-helix-leucine zipper (bHLH-zip) domain located at the N-terminus of the protein. The sequence under the blue line indicates the DUF2014 domain specific to the ER membrane-bound transcription factor Sterol Regulatory Element Binding Proteins (SREBPs). The arrow indicates the amino acid position of the highly conserved tyrosine in the bHLH zipper domain (bHLH-zip). B: Transmembrane domain prediction plots of SreA.