Table 2.
Sample | 〈rDEER〉 (Å)a | W1/2 (Å)a |
---|---|---|
SLAB by itself | 27.5 ± 0.5 | 7.0 ± 0.5 |
SLCD by itself | 26.8 ± 0.4 | 5.2 ± 0.4 |
SLEF by itself | 26.3 ± 0.4 | 4.3 ± 0.4 |
1:1:4 SLCD/mini TAR RNA/NCp7 | 35.1 ± 0.6 | 10.8 ± 1.0 |
1:1:4 SLEF/mini TAR RNA/NCp7b | 34.8 ± 0.6 | 14.0 ± 1.0 |
1:1:4 SLAB/mini TAR RNA/NCp7 | 76.5 ± 2.0 | 19.5 ± 2.0 |
〈rDEER〉 and W1/2 are the respective experimental interlabel distance and the full peak width at half height of the interlabel distance distribution, as determined experimentally by DEER.
In the presence of a fourfold excess of NCp7 with respect to mini TAR DNA and mini TAR RNA, there is evidence for a broad shoulder in the interlabel distribution that extends above 50 Å separation; it is most notable in the SLEF sample.