Table 4.
Effect of cisplatin and/or Quercetin on antioxidant enzyme activities in kidney homogenate of albino rat.
| Parameter | Control | QE | Cisplatin | Cisplatin + QE |
|---|---|---|---|---|
| SOD (μmol/mg.wt.w/min) | 20.3 ± 1.8 | 23 ± 2 | 8.2 ± 2⁎⁎# | 18 ± 1.2 |
| CAT (μmol/H2O2 decomposed/mg.wt.w/min) | 798 ± 15.2 | 801 ± 4.5 | 480 ± 10⁎⁎## | 760 ± 25 |
| GR (U/mg.wt.w) | 5.3 ± 0.3 | 5.6 ± 0.6 | 2.8 ± 0.3⁎⁎.# | 5 ± 0.5 |
| GPx (μmol/mg.wt.w/min) | 130 ± 10 | 135 ± 5 | 46 ± 6⁎⁎# | 120 ± 10 |
SOD, superoxide dismutase; CAT, catalase enzyme; GR, glutathione reductase; GPx, glutathione peroxidase; wt.w, wet weight tissue. ∗∗∗p < 0.001, statistically significant difference from control group.
⁎⁎
p < 0.01, statistically significant difference from control group.
#
p < 0.05, statistically significant difference from cisplatin + QE group.
##
p < 0.01, statistically significant difference from cisplatin + QE group.