TABLE 3.
Quintile 1 | Quintile 2 | Quintile 3 | Quintile 4 | Quintile 5 | P-trend2 | P-interaction | |
DASH | |||||||
BMI <30 | |||||||
Deaths, n | 228 | 262 | 223 | 183 | 192 | ||
HR (95% CI) | 1.00 (ref) | 0.72 (0.60, 0.86) | 0.69 (0.57, 0.84) | 0.64 (0.52, 0.79) | 0.65 (0.52, 0.80) | <0.001 | |
BMI ≥30 | 0.04 | ||||||
Deaths, n | 108 | 171 | 134 | 102 | 75 | ||
HR (95% CI) | 1.00 (ref) | 1.20 (0.94, 1.54) | 1.14 (0.88, 1.49) | 1.02 (0.76, 1.36) | 0.99 (0.72, 1.37) | 0.71 | |
Western | |||||||
BMI <30 | |||||||
Deaths, n | 200 | 195 | 200 | 209 | 284 | ||
HR (95% CI) | 1.00 (ref) | 1.06 (0.87, 1.30) | 1.11 (0.91, 1.35) | 1.19 (0.98, 1.46) | 1.54 (1.27, 1.87) | <0.001 | |
BMI ≥30 | 0.05 | ||||||
Deaths, n | 83 | 116 | 129 | 126 | 136 | ||
HR (95% CI) | 1.00 (ref) | 1.16 (0.87, 1.54) | 1.24 (0.94, 1.64) | 1.15 (0.87, 1.53) | 1.10 (0.82, 1.46) | 0.74 | |
DASH | |||||||
Never smokers | |||||||
Deaths, n | 111 | 163 | 158 | 130 | 127 | ||
HR (95% CI) | 1.00 (ref) | 0.93 (0.73, 1.19) | 1.00 (0.78, 1.28) | 0.93 (0.71, 1.21) | 0.96 (0.72, 1.26) | 0.78 | |
Ever smokers | 0.01 | ||||||
Deaths, n | 225 | 269 | 199 | 153 | 140 | ||
HR (95% CI) | 1.00 (ref) | 0.78 (0.65, 0.93) | 0.68 (0.56, 0.83) | 0.58 (0.47, 0.72) | 0.57 (0.45, 0.72) | <0.001 | |
Western | |||||||
Never smokers | |||||||
Deaths, n | 137 | 152 | 149 | 130 | 121 | ||
HR (95% CI) | 1.00 (ref) | 1.19 (0.95, 1.51) | 1.20 (0.95, 1.52) | 1.18 (0.93, 1.52) | 1.20 (0.93, 1.55) | 0.19 | |
Ever smokers | 0.07 | ||||||
Deaths, n | 144 | 158 | 180 | 205 | 299 | ||
HR (95% CI) | 1.00 (ref) | 1.04 (0.83, 1.31) | 1.17 (0.94, 1.46) | 1.26 (1.01, 1.57) | 1.59 (1.29, 1.96) | <0.001 | |
DASH | |||||||
Vigorous exercise <3 h/wk | |||||||
Deaths, n | 326 | 416 | 323 | 252 | 232 | ||
HR (95% CI) | 1.00 (ref) | 0.86 (0.74, 0.99) | 0.77 (0.66, 0.91) | 0.69 (0.58, 0.82) | 0.70 (0.58, 0.84) | <0.001 | |
Vigorous exercise ≥3 h/wk | 0.33 | ||||||
Deaths, n | 9 | 15 | 30 | 27 | 33 | ||
HR (95% CI) | 1.00 (ref) | 0.84 (0.36, 1.94) | 1.32 (0.61, 2.86) | 1.19 (0.54, 2.62) | 0.95 (0.43, 2.10) | 0.99 | |
Western | |||||||
Vigorous exercise <3 h/wk | |||||||
Deaths, n | 252 | 275 | 306 | 315 | 401 | ||
HR (95% CI) | 1.00 (ref) | 1.06 (0.89, 1.26) | 1.17 (0.98, 1.38) | 1.20 (1.01, 1.42) | 1.41 (1.20, 1.67) | <0.001 | |
Vigorous exercise ≥3 h/wk | 0.43 | ||||||
Deaths, n | 27 | 31 | 23 | 19 | 14 | ||
HR (95% CI) | 1.00 (ref) | 1.56 (0.92, 2.66) | 1.43 (0.80, 2.57) | 1.42 (0.76, 2.64) | 1.20 (0.60, 2.39) | 0.53 | |
DASH | |||||||
Age <55 y | |||||||
Deaths, n | 213 | 212 | 154 | 100 | 65 | ||
HR (95% CI) | 1.00 (ref) | 0.84 (0.69, 1.02) | 0.87 (0.71, 1.08) | 0.80 (0.63, 1.03) | 0.69 (0.52, 0.93) | 0.01 | |
Age ≥55 y | 0.44 | ||||||
Deaths, n | 123 | 221 | 203 | 185 | 202 | ||
HR (95% CI) | 1.00 (ref) | 0.88 (0.70, 1.10) | 0.79 (0.63, 1.00) | 0.72 (0.57, 0.91) | 0.75 (0.59, 0.96) | 0.01 | |
Western | |||||||
Age <55 y | |||||||
Deaths, n | 89 | 121 | 151 | 171 | 212 | ||
HR (95% CI) | 1.00 (ref) | 1.20 (0.91, 1.58) | 1.36 (1.04, 1.77) | 1.40 (1.08, 1.82) | 1.55 (1.20, 2.01) | <0.001 | |
Age ≥55 y | 0.22 | ||||||
Deaths, n | 194 | 190 | 178 | 164 | 208 | ||
HR (95% CI) | 1.00 (ref) | 1.07 (0.87, 1.30) | 1.07 (0.87, 1.32) | 1.07 (0.87, 1.33) | 1.28 (1.04, 1.57) | 0.03 | |
DASH | |||||||
Education <16 y | |||||||
Deaths, n | 236 | 255 | 216 | 157 | 117 | ||
HR (95% CI) | 1.00 (ref) | 0.79 (0.66, 0.95) | 0.85 (0.70, 1.04) | 0.75 (0.61, 0.93) | 0.67 (0.53, 0.86) | 0.002 | |
Education ≥16 y | 0.19 | ||||||
Deaths, n | 98 | 177 | 141 | 125 | 150 | ||
HR (95% CI) | 1.00 (ref) | 1.01 (0.79, 1.30) | 0.82 (0.63, 1.07) | 0.75 (0.57, 1.00) | 0.86 (0.65, 1.13) | 0.06 | |
Western | |||||||
Education <16 y | |||||||
Deaths, n | 148 | 156 | 195 | 203 | 279 | ||
HR (95% CI) | 1.00 (ref) | 1.02 (0.82, 1.28) | 1.13 (0.91, 1.41) | 1.14 (0.92, 1.42) | 1.33 (1.08, 1.64) | 0.003 | |
Education ≥16 y | 0.93 | ||||||
Deaths, n | 135 | 153 | 133 | 131 | 139 | ||
HR (95% CI) | 1.00 (ref) | 1.18 (0.94, 1.49) | 1.18 (0.93, 1.51) | 1.27 (0.99, 1.63) | 1.43 (1.11, 1.84) | 0.006 |
DASH, Dietary Approaches to Stop Hypertension; ref, reference.
Derived from test for linear trend, modeling the median value for each quintile as a continuous variable.