Probability of survival free from appropriate ICD shocks (top) and all-cause mortality (bottom) as a function of a combined biomarker score. The combined score was created by adding the quartile rank for CRP, IL-6, TNF-αRII, pro-BNP, and cTnT. The median score was 12 (range 5 to 20). The proportion of participants with scores 5 to 9, 10 to 14, and 15 to 20 were 27.2, 38.1, and 27.2%, respectively.