Table 1.
Baseline characteristics of participants, by appropriate ICD shock
| Characteristic | Total (n = 1189) |
No appropriate ICD shock (n=1052) |
Appropriate ICD shock (n = 137) |
p-value |
|---|---|---|---|---|
| Age (year) | 60.6 (12.7) | 60.7 (12.8) | 59.9 (11.6) | 0.46 |
| Sex | 0.01 | |||
| Male | 867 (72.9) | 755 (71.8) | 112 (81.8) | |
| Female | 322 (27.1) | 297 (28.2) | 25 (18.2) | |
| Race | 0.008 | |||
| White | 679 (57.1) | 584 (55.5) | 95 (69.3) | |
| Black | 477 (40.1) | 437 (41.5) | 40 (29.2) | |
| Other | 33 (2.8) | 31 (2.9) | 2 (1.5) | |
| Smoking | 0.02 | |||
| Never | 398 (33.5) | 367 (34.9) | 31 (22.6) | |
| Former | 541 (45.5) | 469 (44.6) | 72 (52.6) | |
| Current | 250 (21.0) | 216 (20.5) | 34 (24.8) | |
| Body mass index (kg/m2) | 29.8 (6.5) | 29.6 (6.6) | 30.8 (6.2) | 0.05 |
| Ejection fraction (%) | 22.3 (7.4) | 22.4 (7.4) | 21.6 (7.5) | 0.27 |
| Heart rate (beats/min) | 76.4 (17.1) | 76.9 (17.3) | 72.3 (14.4) | 0.004 |
| QTc (ms) | 459.8 (43.4) | 459.7 (43.8) | 460.8 (40.0) | 0.77 |
| QRS (ms) | 118.2 (30.2) | 117.9 (30.3) | 120.5 (28.8) | 0.36 |
| NHYA class | 0.54 | |||
| Class I | 196 (16.5) | 168 (16.0) | 28 (20.4) | |
| Class II | 524 (44.1) | 467 (44.4) | 57 (41.6) | |
| Class III | 464 (39.0) | 413 (39.3) | 51 (37.2) | |
| Class IV | 5 (0.4) | 4 (0.4) | 1 (0.7) | |
| Cardiomyopathy | 0.71 | |||
| Non-ischemic | 547 (46.0) | 486 (46.2) | 61 (44.5) | |
| Ischemic | 642 (54.0) | 566 (53.8) | 76 (55.5) | |
| Atrial fibrillation | 312 (26.2) | 280 (26.6) | 32 (23.4) | 0.42 |
| Diabetes | 414 (34.8) | 369 (35.1) | 45 (32.8) | 0.61 |
| Hypertension | 747 (62.8) | 674 (64.1) | 73 (53.3) | 0.01 |
| Chronic kidney disease | 360 (30.3) | 331 (31.5) | 29 (21.2) | 0.03 |
| Medications | ||||
| ASA | 781 (65.7) | 689 (65.5) | 92 (67.2) | 0.70 |
| ACE-I/ARB | 850 (71.5) | 748 (71.1) | 102 (74.5) | 0.41 |
| Beta blocker | 1061 (89.2) | 943 (89.6) | 118 (86.1) | 0.21 |
| Diuretics | 857 (72.1) | 757 (72.0) | 100 (73.0) | 0.80 |
| Aldosterone antagonist | 302 (25.4) | 267 (25.4) | 35 (25.5) | 0.97 |
| Device type | 0.74 | |||
| Single | 655 (55.1) | 574 (54.6) | 81 (59.1) | |
| BiV (no atrial lead) | 26 (2.2) | 24 (2.3) | 2 (1.5) | |
| Dual | 211 (17.7) | 189 (18.0) | 22 (16.1) | |
| Dual/BiV | 297 (25.0) | 265 (25.2) | 32 (23.4) | |
| Lowest rate of cutoff (beats/min) | 185.2 (14.6) | 185.5 (14.7) | 182.9 (13.4) | 0.05 |
| ATP used | 694 (58.4) | 627 (59.6) | 67 (48.9) | 0.02 |
Values are number (%), or mean (SD)