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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2014 Oct 1;7(6):1084–1091. doi: 10.1161/CIRCEP.113.001705

Table 3.

Number of events and incidence rates (number of events/total person-years at risk) by levels of biomarkers.

Biomarkers Appropriate ICD shock
All-cause mortality
Number of events Person-years Incidence rate (%) Number of events Person-years Incidence rate (%)


hs-CRP (μg/mL)
 1: ≤1.6 27 1143.7 2.4 54 1495.1 3.6
 2: 1.7–4.4 36 1076.3 3.3 60 1430.5 4.2
 3: 4.5–10.6 36 955.2 3.8 85 1344.6 6.3
 4: >10.6 31 860.4 3.6 115 1297.1 8.8
IL-6 (pg/mL)
 1: ≤1.1 18 1020.6 1.8 34 1342.5 2.5
 2: 1.2–2.0 35 1064.9 3.3 56 1473.5 3.8
 3: 2.1–4.3 35 1048.6 3.3 93 1423.7 6.5
 4: >4.3 42 905.2 4.6 131 1332 9.8
IL-10 (pg/mL)
 1: ≤0.9 31 1157.1 2.7 69 1607.1 4.3
 2: 1.0–1.4 41 984.2 4.2 71 1343.6 5.3
 3: 1.5–2.8 29 899.6 3.2 88 1263.3 6.9
 4: >2.8 28 993.8 2.8 86 1348.2 6.4
TNF-α rec II (pg/mL)
 1: ≤2318.8 36 1133.3 3.2 48 1589.6 3.0
 2: 2318.9–3160.4 33 1099.5 3.0 58 1491.4 3.9
 3: 3160.5–4754.1 36 1014 3.6 86 1386 6.1
 4: >4754.1 25 792.5 3.2 122 1104.7 11.0
Pro-BNP (ng/mL)
 1: ≤1.7 22 1048.1 2.1 30 1413.8 2.1
 2: 1.8–2.6 40 1122.2 3.6 58 1546.1 3.8
 3: 2.7–4.1 41 1075.3 3.8 79 1455.2 5.4
 4: >4.1 25 772.8 3.2 146 1127.2 12.9
cTnT (ng/mL)
 1:00 43 1918.3 2.2 75 2469 3.0
 2: 0.001–0.017 37 793.8 4.7 53 1199.6 4.4
 3: 0.018–0.050 23 741 3.1 83 1019.3 8.0
 4: >0.050 26 577.7 4.5 103 869.9 11.8
cTnI (ng/mL)
 1:00 35 1248.5 2.8 72 1623.7 4.4
 2: 0.001–0.015 26 921.9 2.8 67 1256.1 5.3
 3: 0.016–0.057 30 899.4 3.3 77 1286.1 6.0
 4: >0.057 34 865.2 3.9 89 1246.9 7.1
CK-MB (ng/mL)
 1: ≤1.7 26 991.8 2.6 62 1365.9 4.5
 2: 1.8–2.5 30 968.4 3.1 77 1328.5 5.8
 3: 2.6–4.1 32 1000.9 3.2 75 1388.6 5.4
 4: >4.1 37 973.9 3.8 91 1329.8 6.8
Myoglobin (ng/mL)
 1:00 22 1070.7 2.1 87 1625.1 5.3
 2: 0.1–21.3 31 876 3.5 46 1163.1 4.0
 3: 21.4–25.2 29 803.8 3.6 74 1067.4 6.9
 4: >25.2 32 835.6 3.8 77 1109.4 6.9