. Author manuscript; available in PMC: 2016 Jan 31.

Published in final edited form as: Clin Immunol. 2014 Dec 5;156(2):119–127. doi: 10.1016/j.clim.2014.11.006

Table 2. METRNL gene expression in different human skin diseases.

Q-PCR analysis show a statistically significant up-regulation of Metrnl in Psoriasis (p<0.002), Atopic Dermatitis (p<0.034), Prurigo Nodularis (p<0.045) and Actinic Keratosis (p<0.017).

Diseases	Patients^*	Healthy Controls ^*	P value
Inflammatory
Atopic Dermatitis	685.3 (523.6–744.2)	436.3 (230.6–630.1)	0.034
Psoriasis	1024 (869.8–1176.0)	436.3 (230.6–630.1)	0.002
Prurigo Nodularis	646.9 (515.4–744.2)	436.3 (230.6–630.1)	0.045
Lupus Erythematous	414.8 (342.4–564)	436.3 (230.6–630.1)	0.755
Lichen Planus	499.7 (453.4–586.7)	436.3 (230.6–630.1)	0.427
Neoplastic
Actinic Keratosis	739.7 (608.7–1167.8)	436.3 (230.6–630.1)	0.017
Basal Cell Carcinoma	411.5 (189.5–624.5)	436.3 (230.6–630.1)	0.784
Squamous Cell Carcinoma	328.5 (268.4–613.9)	436.3 (230.6–630.1)	0.949

Median; Interquartile range in parentheses. Healthy controls N=10; Patients, a minimum N=6 was used.