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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: J Hepatol. 2014 Oct 23;62(3):599–606. doi: 10.1016/j.jhep.2014.10.024

Fig. 1. Dietary nutrient content has a strong influence on liver tumor burden and multiplicity in mice treated with DEN.

Fig. 1

(A) Diagram of study design. Tumor incidence (B), average tumor burden (C), and multiplicity (D) of DEN-treated mice at 32 weeks of age. Data presented as mean±SEM. * indicates a significant difference compared to NC group, p<0.05 (n=5–11). (E) Histological classification of tumors observed (n=4–6). HCC=hepatocellular carcinoma, HCA=hepatocellular adenoma. (F) Representative images of livers of DEN-treated mice and a liver from an age-matched mouse fed NC (NC no DEN) shown for comparison.