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. 2014 Nov 10;10(2):421–432. doi: 10.1021/cb500828m

Figure 1.

Figure 1

Phospholipase D. (A) Sequences of HKD-containing mammalian PLD1 and PLD2, P. aeruginosa PldA, and the non-HKD containing NAPE-PLD, highlighting the divergent sequences and overall disparate homology. (B) Schematic of the enzyme-catalyzed reactions of these PLDs that result in phosphatidic acid (PA) production and diverse substrates.