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Single-point screen of analogues 11. (A) Preliminary library screening approach for mammalian PLD inhibitor identification using a mass spectroscopy-based assay; (B) desketoraloxifene analogue 11 inhibition of cellular PLD1 (PMA stimulated Calu-1 cells) or (C) cellular PLD2 (HEK293-PLD2 cells) tested at 10 μg/mL.
