Table 2. Reactivity of 489 in NCPs Containing Histone H4 Variants.
histone H4 variant | % ICL yielda | % DPC yielda |
---|---|---|
WT | 23.8 ± 2.9 | 49.7 ± 3.1 |
K16A | 24.7 ± 0.5 | 50.4 ± 0.6 |
K20A | 24.8 ± 0.5 | 50.3 ± 1.0 |
K16A, K20A | 24.8 ± 2.1 | 51.5 ± 1.5 |
K5A, K8A, K12A | 29.1 ± 1.5 | 50.7 ± 0.7 |
H18A | b | 43.5 ± 3.7 |
K5R, K8R, K12R, K16R, K20R | b | 43.8 ± 1.1 |
K5R, K8R, K12R, K16R, K20R, H18A | b | 24.2 ± 1.5 |
H4 deletion | 21.2 ± 2.1 | 27.3 ± 3.0 |
Values are the average of three independent reactions ± SD.
Not determined.