Fig. 1.

Human mast cell line LAD2 cells are responsive to virus infection by inducing anti-viral type I interferons. LAD2 cells were stimulated with the indicated concentrations of VSV for 24 h (a) or with VSV (MOI = 100) for the indicated times (b). The levels of mRNA for IFN-α and IFN-β were determined by quantitative PCR. The columns present the mean ± SD of 3 separate experiments. *p < 0.05; **p < 0.01; ***p < 0.001 compared with un-stimulated cells