Fig. 5.

In the prepulse inhibition of the acoustic startle response (PPI) test, ACPC affected prepulse inhibition response neither in (a) naive animals, suggesting the lack of psychotomimetic effects, nor in (b) ketamine-induced PPI disturbed conditions, suggesting the lack of antipsychotic-like effects. Values represent the mean (±SEM) percentage of prepulse inhibition. *P < 0.05, vs. vehicle control at a given prepulse intensity expressed in decibel. N = 4–15 rats per dose (naive animals) and 4–11 rats per dose (ketamine-disturbed conditions)