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. 2014 Sep 27;232(6):1025–1038. doi: 10.1007/s00213-014-3738-4

Table 1.

The effects of treatments on the exploration of objects A1 and A2 used during test 1 in the novel object recognition test

Treatment (N) Object A1 exploration (s) Object A2 exploration (s)
ITI = 24 h, undisturbed conditions
 Vehicle (10) 12.66 ± 1.07 11.70 ± 1.13
 ACPC 200 mg/kg (10) 10.84 ± 0.67 11.25 ± 1.20
 ACPC 400 mg/kg (10) 11.31 ± 1.38 12.15 ± 1.08
 Statistics of two-way mixed-design ANOVA

Treatment: F(2.27) = 0.33; NS

Object: F(1.27) = 0.02; NS

Treatment × object: F(2.27) = 0.88; NS

ITI = 1 h, ketamine disturbed
 Vehicle (10) 8.37 ± 0.78 9.43 ± 0.62
 VEH + KET 20 mg/kg (9) 10.38 ± 0.95 12.09 ± 1.20
 ACPC 400 + KET 20 mg/kg (10) 9.15 ± 0.68 10.58 ± 1.06
 Statistics of two-way mixed-design ANOVA

Treatment: F(2.26) = 2.50; NS

Object: F(1.26) = 5.44; P < 0.05

Treatment × object: F(2.26) = 0.90; NS

ITI = 1 h, PCP disturbed
 Vehicle (8) 10.83 ± 0.73 9.75 ± 0.59
 VEH + PCP 5 mg/kg (9) 9.23 ± 1.13 9.61 ± 0.82
 ACPC 200 + PCP 5 mg/kg (10) 8.85 ± 1.27 8.73 ± 1.09
 ACPC 400 + PCP 5 mg/kg (10) 9.89 ± 1.46 10.01 ± 0.94
 Statistics of two-way mixed-design ANOVA

Treatment: F(3.33) = 0.50; NS

Object: F(1.33) = 0.08; NS

Treatment × object: F(3.33) = 0.26; NS

ITI = 1 h, PCP disturbed
 Vehicle (9) 8.76 ± 1.08 8.54 ± 0.52
 VEH + PCP 5 mg/kg (9) 7.31 ± 1.00 7.60 ± 1.13
 Clozapine 1 + PCP 5 mg/kg (11) 6.95 ± 1.18 9.08 ± 0.86
 Statistics of two-way mixed-design ANOVA

Treatment: F(2.26) = 0.53; NS

Object: F(1.26) = 1.03; NS

Treatment × object: F(2.26) = 1.05; NS