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. 2014 Sep 27;232(6):1025–1038. doi: 10.1007/s00213-014-3738-4

Table 3.

Effects of ACPC and MK-801 on omissions (total number of trials omitted during a 100-trial session), correct response latency (time from the stimulus onset to a correct response), reward latency (time from a correct response to the retrieval of food from the magazine), and perseverant responses (total number of responses emitted after a correct response has been made) in the five-choice serial reaction time task. Values represent the mean (±SEM). N = 9–12 rats per dose (ACPC study) and 7–8 rats per dose (MK-801 study)

Treatment Omissions (n) Latency correct (s) Latency reward (s) Perseverant (n)
Vehicle 12.9 ± 2.5 0.96 ± 0.07 1.73 ± 0.08 1.6 ± 0.7
ACPC 200 mg/kg 10.9 ± 1.6 0.99 ± 0.08 1.56 ± 0.13 1.8 ± 0.8
ACPC 400 mg/kg 11.8 ± 1.6 0.81 ± 0.07 1.53 ± 0.11 2.0 ± 0.9
F(2.29) = 0.27 F(2.29) = 1.85 F(2.29) = 0.84 F(2.29) = 0.07
NS NS NS NS
Vehicle 13.5 ± 2.6 0.93 ± 0.04 1.80 ± 0.1 3.6 ± 0.8
MK-801 12 μg/kg 8.1 ± 1.8 0.75 ± 0.03* 1.46 ± 0.08* 2.8 ± 1.4
MK-801 25 μg/kg 13.6 ± 2.0 0.78 ± 0.04* 1.47 ± 0.07* 2.3 ± 0.8
MK-801 50 μg/kg 18.0 ± 4.9 0.84 ± 0.04 1.39 ± 0.06* 1.1 ± 0.7
F(3.27) = 1.81 F(3.27) = 4.25 F(3.27) = 4.91 F(3.27) = 1.14
NS P < 0.05 P < 0.01 NS

*P < 0.05, vs. vehicle