Table 2.
EGR-1 | T-bet | GATA-3 | TGF-β | |||||
---|---|---|---|---|---|---|---|---|
ΔΔCt 1 | 2 -ΔΔCt1 | ΔΔCt 1 | 2 -ΔΔCt1 | ΔΔCt 1 | 2 -ΔΔCt1 | ΔΔCt 2 | 2 -ΔΔCt2 | |
Stage I-II | −0.120 ± 0.67 | 1.09 ± 0.23 | −2.496 ± 0.568 | 5.65 ± 1.05 | −3.742 ± 0.714 | 13.33 ± 2.65 | 0.723 ± 0.793 | 0.605 ± 0.51 |
Stage III-IV | −2.952 ± 0.851 | 7.69 ± 2.10 | −4.099 ± 1.272 | 17.24 ± 4.23 | −5.143 ± 1.632 | 35.71 ± 12.41 | 1.337 ± 0.931 | 0.395 ± 0.46 |
P | 0.008* | 0.068 | 0.144 | 0.092 |
Note: ΔΔCt1 = ΔCttarget gene in control-ΔCttarget gene in patients,2-ΔΔCt1 indicates the fold decrease in the expression of target genes in patients compared to controls. ΔΔCt2 = ΔCt TGF-β in patient-ΔCt TGF-β in control, 2-ΔΔCt2 indicates the fold increase in TGF-β expression in patients compared to controls. *indicates that there is significant difference between two groups.