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. 2014 Dec 24;14:85. doi: 10.1186/s12935-014-0085-9

Table 2.

Differential gene expression between DLBCL patients with different disease stages at baseline

EGR-1 T-bet GATA-3 TGF-β
ΔΔCt 1 2 -ΔΔCt1 ΔΔCt 1 2 -ΔΔCt1 ΔΔCt 1 2 -ΔΔCt1 ΔΔCt 2 2 -ΔΔCt2
Stage I-II −0.120 ± 0.67 1.09 ± 0.23 −2.496 ± 0.568 5.65 ± 1.05 −3.742 ± 0.714 13.33 ± 2.65 0.723 ± 0.793 0.605 ± 0.51
Stage III-IV −2.952 ± 0.851 7.69 ± 2.10 −4.099 ± 1.272 17.24 ± 4.23 −5.143 ± 1.632 35.71 ± 12.41 1.337 ± 0.931 0.395 ± 0.46
P 0.008* 0.068 0.144 0.092

Note: ΔΔCt1 = ΔCttarget gene in control-ΔCttarget gene in patients,2-ΔΔCt1 indicates the fold decrease in the expression of target genes in patients compared to controls. ΔΔCt2 = ΔCt TGF-β in patient-ΔCt TGF-β in control, 2-ΔΔCt2 indicates the fold increase in TGF-β expression in patients compared to controls. *indicates that there is significant difference between two groups.