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. 2015 Feb 22;17(1):23. doi: 10.1186/s12968-015-0128-y

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© Lopez et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Representative perfusion maps of each study group demonstrate the difference in perfusion patterns with exercise (A, C) compared to cuff occlusion hyperemia (B, D). During exercise perfusion is limited to the anterior compartment, lateral compartment (arrows) and gastrocnemius (arrow heads). Post-occlusion hyperemia tends to be more diffuse in healthy volunteers (B). However, in PAD patients (D) reactive hyperemia is of lesser magnitude and extent, generally limited to the soleus muscle (outlined).