Table 2.
Univariate analysis of prognostic factors for DFS and OS
| Factor | Classification | p value (DFS) | p value (OS) |
|---|---|---|---|
| Sex | Female | ||
| Male | 0.9818 | 0.8802 | |
| Age | <65 | ||
| ≥65 | 0.5093 | 0.8196 | |
| Cancer location | Right | ||
| Transverse | 0.2048 | 0.0534 | |
| Descending | 0.2056 | 0.5503 | |
| Sigmoid and rectosigmoid | 0.7813 | 0.9634 | |
| Lymphovascular invasion | Negative | ||
| Positive | 0.4643 | 0.2176 | |
| Neural invasion | Negative | ||
| Positive | 0.3234 | 0.6679 | |
| Histology (differentiation ) | Well | ||
| Moderately | 0.5575 | 0.9728 | |
| Poorly | 0.9001 | 0.894 | |
| Signet ring cell | 0.1424 | 0.1516 | |
| Mucinous cell | 0.8841 | 0.8773 | |
| WBC | 4,000 ~ 10,000 × 106/L | ||
| <4,000 × 106/L | 0.8888 | 0.9328 | |
| Hgb | Normal | ||
| Anemia | 0.0019 | 0.0143 | |
| PLT | 140 ~ 440 × 109/L | ||
| Thrombocytopenia | 0.0444 | 0.0485 | |
| >440 × 109/L | 0.6451 | 0.7521 | |
| Albumin | 3.8 ~ 5.3 g/dL | ||
| <3.8 g/dL | 0.3055 | 0.0298 | |
| LDH | 129 ~ 240 U/L | ||
| >240 U/L | 0.1801 | 0.2756 | |
| Total bilirubin | 0.2 ~ 1.0 mg/dL | ||
| >1.0 mg/dL | 0.2247 | 0.8442 | |
| AST | 10 ~ 33 U/L | ||
| >33 U/L | 0.1258 | 0.4506 | |
| ALT | 4 ~ 50 U/L | ||
| >50 U/L | 0.4121 | 0.7752 | |
| Protein | 6.7 ~ 8.3 g/dL | ||
| <6.7 g/dL | 0.3451 | 0.3746 | |
| T stage | 1 | ||
| 2 | |||
| 3 | |||
| 4 | 0.0018 | 0.005 | |
| N stage | 0 | ||
| 1 | 0.2954 | 0.4345 | |
| 2 | 0.6658 | 0.1171 | |
| Preoperative CEA | ≤5 ng/mL | ||
| >5 ng/mL | 0.4768 | 0.2144 | |
| Postoperative CEA | ≤5 ng/mL | ||
| >5 ng/mL | 0.0585 | 0.0019 | |
| ASA score | 1 | ||
| 2 | 0.31 | 0.7768 | |
| 3 | 0.7646 | 0 | |
| Neutropenia | Absent | ||
| Present | 0.7597 | 0.1927 | |
| GI Symptom (diarrhea, nausea, anorexia) | Absent | ||
| Present | 0.6714 | 0.508 |
ALT, alanine aminotransferase; ASA, American Society of Anesthesiologists; AST, aspartate aminotransferase; CEA, carcinoembryonic antigen; GI symptoms, gastrointestinal symptoms (diarrhea, constipation, anorexia); Hgb, hemoglobin; LDH, lactate dehydrogenase; PLT, platelet; WBC, white blood cell.