Table 6.
Functional enrichment classification of identified host-specific proteins using DAVID bioinformatics tool
| Enrichment score + | Protein count (%) | Protein ID | P value | ||
|---|---|---|---|---|---|
| Biological process | Regulation of response to external stimulus | 2.3 | 3 (27.27) | AHSG, C3, HRG | 4.69e-3 |
| Cellular iron ion homeostasis | 2.13 | 3 (27.27) | HAP, HPX, TF | 1.81e-4 | |
| Iron ion homeostasis | 2.13 | 3 (27.27) | HAP, HPX, TF | 2.45e-4 | |
| Cellular di-, tri-valent inorganic cation homeostasis | 2.13 | 3 (27.27) | HAP, HPX, TF | 9.34e.3 | |
| Di-, tri-valent inorganic cation homeostasis | 2.13 | 3 (27.27) | HAP, HPX, TF | 1.03e-2 | |
| Cellular cation homeostasis | 2.13 | 3 (27.27) | HAP, HPX,TF | 1.16e-2 | |
| Molecular function | Endopeptidase inhibitor activity | 2.3 | 3 (27.27) | AHSG,C3, HRG | 3.32e-3 |
| Peptidase inhibitor activity | 2.3 | 3 (27.27) | AHSG, C3, HRG | 3.69e-3 | |
| Enzyme inhibitor activity | 2.3 | 3 (27.27) | AHSG, C3, HRG | 1.11e-2 | |
| Cellular component | Extracellular region | 8.11 | 11 (100) | A1BG, AHSG, APOA1, AZGP1, C3, FGG, HAP, HPX, HRG, LRG1, TF | 2.66e-11 |
| Secretory granule | 2.31 | 4 (36.36) | APOA1, FGG, HRG, TF | 3.06e-4 | |
| Cytoplasmic membrane-bounded vesicle | 2.31 | 4 (36.36) | APOA1, FGG, HRG, TF | 7.58e-3 | |
| Membrane-bounded vesicle | 2.31 | 4 (36.36) | APOA1, FGG, HRG, TF | 8.29e-3 | |
| Cytoplasmic vesicle | 2.31 | 4 (36.36) | APOA1, FGG, HRG, TF | 1.16e-2 |
+The classification stringency was set to high.