Table 1.
Demographic and clinical characteristics of chronically HIV-1-infected patients and HIV seronegative healthy individuals
| Item | Healthy individuals (n = 21) (A) | Naïve HIV-1-infected patients (n = 58) (B) | Treated HIV-1-infected patients (n = 5) (C) | A vs B | A vs C |
|---|---|---|---|---|---|
| p values | p values | ||||
| Males, n (%) | 13 (61.90) | 43 (74.13) | 4 (80) | 0.549 | 0.809 |
| Mean age ± SD (years) | 42.38 ± 11.33 | 39.43 ± 11.84 | 44.25 ± 21.51 | 0.326 | 0.784 |
| Virus subtype | NA | B | B | NA** | NA |
| HIV RNA (copies/ml)* | NA | 34925 (143–1,405,000) | 1446 (80–123,200) | NA | NA |
| CD4+ count (cells/mm3)* | NA | 524 (22–1,200) | 400 (350–895) | NA | NA |
| Time post infection (months)* | NA | 12 (1–168) | 84 (12–168) | NA | NA |
| Duration of HAART (years)* | NA | NA | 6.5 (1–13) | NA | NA |
*Data are expressed as median (range).
Differences in demographic characteristics between HIV-1-infected patients and HIV seronegative healthy individuals were evaluated using Student's t and Chi-squared tests.
**NA = not applicable.