Table 2.
Univariate and multivariate analyses related to disease-free survival in 97 colorectal cancer patients
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| Hazard ratio | P value | Hazard ratio | P value | |
| Age | 0.98 (0.94–1.02) | 0.38 | ||
| Gender (F) | 1.42 (0.50–4.04) | 0.51 | ||
| Tumor location (colon vs rectum) | 4.23 (1.49–12.01) | 0.01 | 4.11 (1.42–11.91) | 0.009 |
| Tumor size (≦5 cm) | 0.64 (0.24–1.73) | 0.38 | ||
| Tumor invasion (SI) | 0.52 (0.12–2.28) | 0.39 | ||
| Differentiation (por or muc) | 1.50 (0.20–11.35) | 0.70 | ||
| Lymphatic invasion (ly0, 1 vs ly2, 3) | 1.10 (0.25–4.83) | 0.90 | ||
| Venous invasion (v0, 1 vs v2, 3) | 3.10 (1.00–9.56) | 0.05 | 3.85 (1.15–12.92) | 0.03 |
| Budding | 0.52 (0.19–1.41) | 0.20 | ||
| Number of lymph nodes analyzed (<12) | 1.32 (0.51–3.43) | 0.57 | ||
| HLA expression level (dull or negative) | 3.86 (1.26–11.85) | 0.02 | 5.36 (1.68–17.11) | 0.005 |
| Adjuvant chemotherapy (no) | 0.82 (0.30–2.22) | 0.70 | ||