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. 2015 Jan 27;12:17. doi: 10.1186/s12974-015-0235-6

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© Chen et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Clinical fundus examination of C57Bl/6 J LysM-eGFP mice in normal and diseased state. Fundus images of naïve C57Bl/6 J LysM-eGFP mouse fundus in brightfield (BF) (A) and fluorescent mode (Fluor) (B) appears normal (n =5). Fundus images of C57Bl/6 J LysM-eGFP mouse (n = 4) immunized with IRBP_1–20 on day 14 post-immunization (d14 p.i.) (C-D) and d21 p.i. (E-F) illustrated the peripapillary infiltrates of vasculitis. eGFP, enhanced green fluorescent protein.