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. 2015 Feb 18;15:66. doi: 10.1186/s12885-015-1073-8

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© Jagarlamudi et al.; licensee BioMed Central. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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TK1 activity and protein levels in breast cancer patients and blood donors. (A) STK1 activity distributions in sera from blood donors (•) and patients with breast cancer (■). (B) STK1 protein levels in sera from blood donors (•) and patients with breast cancer (■). (C) Comparison of STK1 activities in sera from blood donors (•) and early-stage (TiS + T1; ■) and late-stage (T2 + T3; ▲) breast cancer patients. (D) Comparison of STK1 protein levels in sera from blood donors (•) and early-stage (TiS + T1; ■) and late stage (T2 + T3; ▲) breast cancer patients. (E) Comparison of STK1 activities in blood donors (•) and non-invasive (DCIS; ■) and invasive (ID + ID/L; ▲) breast cancer patients. (F) Comparison of STK1 protein levels in blood donors (•) and non-invasive (DCIS; ■) and invasive (ID + ID/L) breast cancer patients (▲). The error bars denote standard deviations (SDs). (G) Receiver operating characteristic (ROC) curve of STK1 activity in serum samples from breast cancer patients and from blood donors. (H) ROC curve analysis of STK1 protein levels in sera from blood donors and breast cancer patients.