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. Author manuscript; available in PMC: 2015 Feb 22.
Published in final edited form as: J Immunol. 2012 Jul 23;189(5):2635–2644. doi: 10.4049/jimmunol.1201115

FIGURE 4.

FIGURE 4

Role of Chit1 in bleomycin- and IL-13–induced pulmonary fibrosis and inflammation. (A–C) Two-month-old WT (Chit1+/+) and Chit1−/− were exposed to i.p. bleomycin (Bleo) and pulmonary fibrosis (A), lung collagen content (B), and BAL inflammation (C) were evaluated by Mallory’s trichrome stains, Sircol collagen assays, and BAL cell counts, respectively. (D–F) Evaluation of pulmonary fibrosis (D), collagen content (E), and BAL inflammation (F) in lungs from IL-13 Tg mice with and without Chit1-null mutations. The values in (B), (C), (E), and (F) are the means ± SEM of evaluations in a minimum of four animals. Panels in (A) and (C) are representative of a minimum of five mice per group. Scale bars, 200 μm. *p < 0.05.