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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Pharmacol Biochem Behav. 2015 Jan 3;130:1–8. doi: 10.1016/j.pbb.2014.12.013

Figure 1. Dose-response curves for the effects of chronic nicotine treatment of mice differing in β4 genotype for select tests.

Figure 1

Mean ± SEM (N =4-9) for responses of β4++, β4+− and β−− mice treated with saline, 1.0 mg/kg/hr nicotine or 4.0 mg/kg/hr nicotine as indicated and acutely injected with the indicated nicotine dose. The lines are least squares curve fits of the results as described in the Methods.