Table 2.
Outcomes | MUD N=1173 | MMUD N=274 | UCB N=140 | P-value |
---|---|---|---|---|
% (95% confidence interval) | ||||
Neutrophil recovery | ||||
at 28 days | 94 (92-95) | 94 (90-96) | 66 (57-73) | <0.001 |
at 100 days | 95 (94-96) | 95 (92-97) | 87 (80-92) | 0.023 |
Platelet recovery 3 20 × 109 | ||||
at 100 days | 86 (84-88) | 85 (80-89) | 68 (59-76) | <0.001 |
Acute GvHD (II-IV) | ||||
at 100 days | 37 (35-40) | 49 (43-55) | 26 (19-34) | <0.001 |
Acute GvHD (III-IV) | ||||
at 100 days | 20 (18-22) | 24 (19-29) | 17 (11-23) | 0.17 |
Chronic GvHD | ||||
at 3 years | 51 (48-54) | 48 (42-54) | 22 (15-30) | <0.001 |
Abbreviations: UCB umbilical cord blood, MMUD 1 Ag or 1 allele mismatched unrelated donor, MUD matched unrelated donor, GvHD graft versus host disease