Table 3.
Three-year adjusted probabilities.
| Outcomes | MUD | MMUD | UCB | UCB vs MUD | UCB vs MMUD | MMUD vs MUD |
|---|---|---|---|---|---|---|
| N=1173 | N=274 | N=140 | p-value | p-value | p-value | |
| % (95% confidence interval) | ||||||
| Non relapse mortality | 35 (32-38) | 44 (39-50) | 37 (28-46) | 0.63 | 0.19 | 0.004 |
| Relapse | 33 (30-36) | 25 (20-30) | 30 (22-38) | 0.48 | 0.27 | 0.003 |
| Progression-free survival | 33 (30-36) | 30 (25-35) | 31 (23-39) | 0.72 | 0.81 | 0.35 |
| Overall survival | 43 (40-46) | 37 (32-43) | 41 (33-50) | 0.77 | 0.45 | 0.073 |
Abbreviations: UCB umbilical cord blood, MMUD mismatched unrelated donor, MUD matched unrelated donor, Adjusted probabilities of progression-free survival, overall survival, relapse and non-relapse mortality for the 3 donor groups were based on a stratified Cox regression model. Karnofsky performance score, lymphoma subset, Graft versus host disease prophylaxis and disease status violated the proportionality assumption, and therefore, all the models were stratified on these variables.