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. Author manuscript; available in PMC: 2015 Feb 22.
Published in final edited form as: Obesity (Silver Spring). 2008 Apr 3;16(6):1178–1185. doi: 10.1038/oby.2008.207

Figure 3.

Figure 3

HSD1 expression and reductase activity are positively associated with adipocyte size and obesity (BMI). (a) Correlation between adipocytes size (FCS, expressed as average adipocyte weight (μg lipid/adipocyte)) and HSD1 mRNA levels in omental (Om) and abdominal subcutaneous (Abd sc) human adipose tissue. (b) Correlation between fat cell size (FCS) and % conversion of 3H-cortisone to 3H-cortisol expressed per 105 adipocytes in Om and Abd sc. (c) Correlation of adipocyte size and % conversion of 3H-cortisone to 3H-cortisol per 50 mg of tissue in Om and Abd sc. (d) Correlation between BMI (kg/m2) and 3H-cortisone to 3H-cortisol per 105 adipocytes in Om and Abd sc. Data are from 22 subjects (6 men and 16 women), BMI: 40.6 ± 2.8 (23–64), age: 46 ± 2.8 (19–63). Individual numbers (n) are given on each figure, because not all parameters were measured in all subjects. HSD1, type 1 hydroxysteroid dehydrogenase.